This paper describes the key characteristics of a scientific research expedition designed to rapidly advance scientific knowledge with respect to the nature and origins of Unidentified Anomalous Phenomena (UAP). We present our approach and motivation for conducting the research, along with background information related to the issue. We provide our analysis of potential locations for such an expedition, as well as an analysis of tools (platforms and sensors) that could be used to detect UAP. We also describe a recommended search methodology for obtaining the data needed for a successful mission, as well as other considerations related to the proposed expedition. We conclude with a summary of our recommendations and highlight the importance of this expedition, particularly in relation to improving aerospace safety.